Patent · US Active

Ketoreductase-mediated stereoselective route to alpha chloroalcohols

US9029112B2 · kind B2 · utility

0Cited by

10References

14Claims

0Family size

Assignee

Codexis, Inc. · US

Inventors

Yong Koy Bong · Singapore, SG
Michael Vogel · Saterland, DE
Steven J. Collier · Concord, US
Vesna Mitchell · San Jose, US
Jagadeesh Mavinahalli · Jamkhed, IN

Key dates

Filing date	Jun 24, 2014
Grant date	May 12, 2015
Priority date	—
Expiry date	Jun 24, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y101/01184
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α-chloroalcohols from α-chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.