Neurturin conjugates for pharmaceutical use

US9029323B2 · kind B2 · utility

Assignee

• EVOTEC INTERNATIONAL GmbH · DE

Inventors

• Matthias Austen · Oebisfelde, DE
• Marcus Geese · Oettingen, DE
• Rainer Mussmann · Oebisfelde, DE
• Friedrich Harder · Gettorf, DE
• Thomas Siegmund · Göttingen, DE
• Martin Schneider · Remchingen, DE

Key dates

• Filing date: May 5, 2010
• Grant date: May 12, 2015
• Expiry date: Mar 25, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to neurturin protein products conjugated to polyols and to pharmaceutical compositions comprising neurturin conjugates as active ingredients, preferably PEGylated neurturin conjugates or variants thereof, having increased bioavailability.