Patent · US Active

Radiation sensitization agents for prostate cancer

US9029340B2 · kind B2 · utility

5Cited by

1References

10Claims

0Family size

Assignee

THE JOHNS HOPKINS UNIVERSITY · US

Inventors

Shawn Lupold · Ellicott City, US
Theodore DeWeese · Towson, US
Xiaohua Ni · Baltimore, US
Yonggang Zhang · Suzhou, CN

Key dates

Filing date	Jul 22, 2011
Grant date	May 12, 2015
Priority date	—
Expiry date	Jul 22, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/11
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compositions and methods are provided for sensitizing neoplastic cells to radiotherapy. The invention provides aptamer-inhibitory nucleic acid chimeras that selectively inliibit the expression of radiosensitizing genes in neoplastic cells expressing a cell surface molecule that binds the aptamer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.