Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof
US9029342B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 17, 2013 |
| Grant date | May 12, 2015 |
| Priority date | — |
| Expiry date | Sep 17, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2842
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treating and/or diagnosing pain and the source or type of pain, shock, and/or inflammatory conditions in a subject. A method of using a therapeutically effective amount of a DNA or RNA aptamer that shows high affinity for OLAMs to at least partially treat pain, shock, and/or inflammatory conditions in a subject. The DNA or RNA aptamer that shows high affinity for OLAMs may be coupled to a plasma protein binding compound or a pharmacologically active agent. A method of treating and or diagnosing pain, shock, and/or inflammatory conditions in a subject may include inactivating or preventing at least one linoleic acid metabolite to treat certain conditions (e.g., pain, shock, and/or inflammation) using a DNA or RNA aptamer that shows high affinity for OLAMs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.