Patent · US Active

Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof

US9034303B2 · kind B2 · utility

0Cited by

1References

19Claims

0Family size

Inventors

Vincent R. Zurawski, Jr. · Cambridge, US
David M. Stout · Vernon Hills, US
Theodore J. Nitz · Pottstown, US
Moussa B. H. Youdim · Rockville, US
Orly WEINREB · Haifa, IL

Key dates

Filing date	Aug 12, 2011
Grant date	May 19, 2015
Priority date	—
Expiry date	Oct 21, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

8-Hydroxy-quinoline derivatives and 8-ethers, 8-esters, 8-carbonates, 8-acyloxymethyl, 8-phosphates, (phosphoryloxy)methyl, and 8-carbamates derivatives thereof are described that exhibit iron chelation, neuroprotective, neurorestorative, apoptotic and/or selective MAO-AB inhibitory activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.