Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Valyl-tRNA synthetases

US9034320B2 · kind B2 · utility

Assignees

• aTyr Pharma, Inc. · US
• Pangu BioPharma Limited · CN

Inventors

• Leslie Ann Greene · San Diego, US
• Kyle P. Chiang · Irvine, US
• Fei Hong · San Diego, US
• Alain P. Vasserot · South San Francisco, US
• Jeffry D. Watkins · Encinitas, US
• Cheryl L. Quinn · Minneapolis, US
• Wing-Sze Lo · Hong Kong, CN
• John D. Mendlein · Encinitas, US

Key dates

• Filing date: Apr 29, 2011
• Grant date: May 19, 2015
• Expiry date: Jun 3, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.