G protein coupled receptor protein and use thereof
US9034327B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 7, 2009 |
| Grant date | May 19, 2015 |
| Priority date | — |
| Expiry date | Sep 7, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5041
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are novel GPCR (G Protein Coupled Receptor) proteins and genes encoding the same. Also provided is the use of the proteins and the genes. Particularly, contemplated are a novel GPCR (G Protein Coupled Receptor) polypeptide, a polynucleotide coding for the same, a recombinant vector carrying the polynucleotide or a fragment thereof, host cells transformed with the vector, a transgenic animal infected with the vector. Also, a composition for detecting a cancer marker, comprising an agent capable of measuring the expression level of mRNA or protein of the GPCR polynucleotide, a kit for the diagnosis of cancer, comprising the composition, and a method for detecting the GPCR polypeptide and a gene encoding the polypeptide are provided. Further, a composition for the treatment and prevention of cancer, comprising an oligonucleotide inhibiting the expression of a gene encoding the GPCR polypeptide or an antibody against the GPCR protein, and a method for screening a modulator of the GPCR protein or a cancer therapeutic agent are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.