Patent · US Active

Protofibril selective antibodies and the use thereof

US9034334B2 · kind B2 · utility

3Cited by

23References

4Claims

0Family size

Assignee

BioArctic Neruoscience AB · SE

Inventors

Pär Gellerfors · Lidingö, SE
Lars Lannfelt · Stockholm, SE
Dag Sehlin · Uppsala, SE
Frida Ekholm Pettersson · Uppsala, SE
Hillevi Englund · Uppsala, SE

Key dates

Filing date	Aug 26, 2011
Grant date	May 19, 2015
Priority date	—
Expiry date	Feb 10, 2034

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/387
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to an isolated antibody, or fragment thereof, having high affinity for human Aβ protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.