Systems and methods for measuring translation of target proteins in cells
US9034576B2 · kind B2 · utility
2Cited by
12References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2010 |
| Grant date | May 19, 2015 |
| Priority date | — |
| Expiry date | Oct 14, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/061
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to systems and methods for measuring the rate of translation of a target protein in cells, which are based on the detection of translation of one or more predetermined codon pairs during synthesis of the target protein. The detection is provided by a FRET signal emitted from labeled tRNA molecules which are juxtaposed during synthesis of the protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.