Vasoprotective and cardioprotective antidiabetic therapy

US9034883B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Thomas KLEIN · Radolfzell, DE
• Andreas DAIBER · Scheeßel, DE
• Odd-Eric JOHANSEN · Tvedestrand, NO
• Michael Mark · Biberach an der Riß, DE
• Sanjaykumar PATEL · Teddington, GB
• Hans-Juergen WOERLE · Munich, DE

Key dates

• Filing date: Nov 14, 2011
• Grant date: May 19, 2015
• Expiry date: Nov 14, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.