Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
US9034884B2 · kind B2 · utility
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51References
36Claims
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Key dates
| Filing date | Nov 18, 2011 |
| Grant date | May 19, 2015 |
| Priority date | — |
| Expiry date | Sep 8, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines of Formula I:wherein X, Y, Z, L, A, R5, n, m, and r are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.