Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution
US9040033B2 · kind B2 · utility
7Cited by
1References
16Claims
0Family size
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Key dates
| Filing date | Jun 13, 2011 |
| Grant date | May 26, 2015 |
| Priority date | — |
| Expiry date | Jan 30, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L1/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility active agent and such polymers, the polymers provide increased aqueous concentrations and/or improved physical stability of the active agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.