Patent · US Active

Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use

US9040058B2 · kind B2 · utility

4Cited by

4References

23Claims

0Family size

Assignee

GLAXOSMITHKLINE BIOLOGICALS SA · BE

Inventors

Friedrich Blackkolb · Marburg, DE
Bernd Becker · Bad Endbach, DE
Martha Reith · Rauschenberg, DE
Manfred Isenberg · Marburg, DE
Anne Katrin Hilbert · Gießen, DE

Key dates

Filing date	Nov 9, 2012
Grant date	May 26, 2015
Priority date	—
Expiry date	Nov 9, 2032

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a fermentation medium for cultivating Corynebacterium diphtheriae. The present invention also relates to the use of the fermentation medium in processes for obtaining diphtheria toxin from the Corynebacterium diphtheriae bacteria being cultivated and the preparation of vaccines using the diphtheria toxin obtained in the processes. The present invention further relates to a purification and detoxification processes specifically adapted for preparing a diphtheria toxoid for inclusion into a vaccine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.