Patent · US Active

Cell-based systems for production of methyl formate

US9040266B2 · kind B2 · utility

0Cited by

5References

19Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Christopher A. Voigt · Oakland, US
Travis S. Bayer · San Francisco, US

Key dates

Filing date	Jul 22, 2010
Grant date	May 26, 2015
Priority date	—
Expiry date	Jan 19, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y201/01165
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed is a process in which a recombinant organism, such as a yeast, expressing a heterologous S-adenosylmethionine (SAM)-dependent methyl halide transferase (MHT) protein is combined with a halide and a carbon source in a cultivation medium under conditions in which methyl formate is produced. The cell may genetically modified to express methyl formate synthase, methanol dehydrogenase and/or hydrolytic dehalogenase at levels higher than a cell of the same species that is not genetically modified. The methyl formate may be collected and used in a variety of applications. The halide may be chlorine, bromine or iodine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.