Heterocyclyl pyrazolopyrimidine analogues as selective JAK inhibitors
US9040545B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2011 |
| Grant date | May 26, 2015 |
| Priority date | — |
| Expiry date | Nov 12, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula (I)wherein X1 to X5, Y, Z1 to Z3, and R have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.