Functionalization and purification of molecules by reversible group exchange
US9040678B2 · kind B2 · utility
9Cited by
9References
20Claims
0Family size
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Key dates
| Filing date | Aug 2, 2012 |
| Grant date | May 26, 2015 |
| Priority date | — |
| Expiry date | Mar 12, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H1/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.