Patent · US Active

Methods and compositions for extraction and storage of nucleic acids

US9040679B2 · kind B2 · utility

7Cited by

22References

38Claims

0Family size

Assignee

General Electric Company · US

Inventors

Erik Leeming Kvam · Albany, US
Bing Li · Towaco, US
Brian Christopher Bales · Niskayuna, US

Key dates

Filing date	Aug 16, 2013
Grant date	May 26, 2015
Priority date	—
Expiry date	Aug 16, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/1006
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A solid matrix for the extraction, stabilization, and storage of nucleic acids is provided. At least one protein denaturant, and at least one acid or acid-titrated buffer reagent are impregnated in a dry state therein the matrix; and the matrix is configured to provide an acidic pH on hydration. The matrix is configured to extract nucleic acids from a sample and stabilize the extracted nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the nucleic acids stored in the dry solid matrix are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.