Method and systems for cell-level fish dot counting
US9042631B2 · kind B2 · utility
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2References
24Claims
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Key dates
| Filing date | Mar 25, 2013 |
| Grant date | May 26, 2015 |
| Priority date | — |
| Expiry date | Jul 18, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V20/69
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The invention relates to a computer implemented method and systems for cell level fish dot counting. FISH (fluorescence in situ hybridization) dot counting is the process of enumerating chromosomal abnormalities in the cells which can be used in areas of diagnosis and cancer research. The method comprises in part overlaying images of a biological sample comprising a nuclear counterstain mask and a FISH binary mask. The FISH binary mask is extracted using a multi-level extended h-maxima or h-minima.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.