Method for chemical synthesis of antrocin and use thereof for suppressing non-small cell lung cancer
US9045450B2 · kind B2 · utility
1Cited by
1References
19Claims
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Key dates
| Filing date | Aug 10, 2011 |
| Grant date | Jun 2, 2015 |
| Priority date | — |
| Expiry date | Aug 10, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for preparing antrocin of pharmaceutically acceptable salts thereof via a series of gold-catalyzed cyclization to construct the (6-6-5) tricyclic core frame. The present invention also provides a use of a composition in preparing drugs for suppressing growth of non-small cell lung cancer cells, wherein the composition comprises an effective amount of antrocin or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.