Process for the production of optically-active esters of lactic acid and lactyllactic acid
US9045781B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jul 16, 2012 |
| Grant date | Jun 2, 2015 |
| Priority date | — |
| Expiry date | Jul 16, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/003
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the mixture with an aliphatic alcohol and an enzyme in the presence of a ketone solvent to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer, and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.