Use of icariin and epimedium flavonoids containing icariin to treat diseases associated with myelin sheath lesion

US9050353B2 · kind B2 · utility

Assignee

• XUANWU HOSPITAL CAPITAL MEDICAL UNIVERSITY · CN

Inventors

• Lin Li · 安丰镇, CN
• Linlin Yin · Beijing, CN
• Lili Lin · Bloomington, US
• Lan Zhang · Beijing, CN
• Wen Wang · Xi'an, CN
• Ruyi Zhang · Tuji, CN

Key dates

• Filing date: Jun 7, 2011
• Grant date: Jun 9, 2015
• Expiry date: Oct 10, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

New use of icariin and Epimedium flavaoids containing icariin is provided by the present invention. Specifically, uses of compounds of Formula I or Epimedium containing compounds of formula I, Epimedium flavanoids, or extracts of Epimedium in manufacturing medicaments for treating, preventing, reducing and/or relieving diseases and/or conditoins related to neural myelin sheath impairments, or use of above materials in manufacturing medicaments for relieving demyelination and/or promoting repair of myelin sheath are provided by the present application, wherein, R1 is selected from H, halogen, —C1-6 alkyl, and —C(O)—C1-4 alkyl