Conjugates of synthetic TLR agonists and uses therefor

US9050376B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Dennis A. Carson · Del Mar, US
• Howard B. Cottam · Escondido, US
• Wolfgang Wrasidlo · Village of La Jolla, US
• Christina C.N. Wu · Escondido, US
• Gregory A. Daniels · San Diego, US

Key dates

• Filing date: Jun 19, 2014
• Grant date: Jun 9, 2015
• Expiry date: Jun 19, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/55555
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides TLR agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma.