Bicyclic [5,6] imidazo pyrimodone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
US9051325B2 · kind B2 · utility
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Key dates
| Filing date | Jan 23, 2014 |
| Grant date | Jun 9, 2015 |
| Priority date | — |
| Expiry date | Jan 23, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to bicyclic[5,6]imidazo pyrimidone compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.In one aspect, this invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof,wherein different R groups are defined in the patent application.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.