Avian cytokines and genetic sequences encoding same
US9051369B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 19, 2008 |
| Grant date | Jun 9, 2015 |
| Priority date | — |
| Expiry date | Apr 26, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to novel recombinant polypeptides having avian cytokine properties and to genetic sequences encoding same. More particularly, the present invention is directed to recombinant avian Type III interferon polypeptides, and genetic sequences encoding same, together with cellular expression systems and uses for same. Even more particularly, the present invention is directed to avian interferon-λ (IFN-λ) and functional derivatives, homologues and fragments thereof and to methods of use thereof. The molecules and cells of the present invention are useful in a wide range of applications including, but not limited to, providing a means for the treatment and prophylaxis of disease conditions, in particular avian disease conditions, or for use as an immune response modulator. Also provided are diagnostic means for screening for immune response and screening means for identifying modulators of IFN-λ protein or nucleic acid functionality.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.