Yeast cell for the production of terpenes and uses thereof
US9051587B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 15, 2012 |
| Grant date | Jun 9, 2015 |
| Priority date | — |
| Expiry date | Apr 3, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P5/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a yeast cell, wherein said cell comprises a functional gene coding for soluble hydroxymethylglutaryl-coenzyme-A (HMG-CoA) reductase; one or more gene(s) coding for steryl acyltransferase(s) in said cell are defective or deleted; and said cell is prototrophic for at least histidine, leucine or uracil. Moreover, the present invention relates to the use of said cell for the production of one or more terpene(s). Further, the present invention relates to methods of generating said cell and the production of one or more terperne(s) and a pharmaceutical or cosmetically composition, a lubricant or transformer oil comprising said terpene(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.