Compounds and assays for controlling Wnt activity
US9052324B2 · kind B2 · utility
0Cited by
8References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 2009 |
| Grant date | Jun 9, 2015 |
| Priority date | — |
| Expiry date | Jan 1, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.