Compositions for treating bone defects

US9056150B2 · kind B2 · utility

Assignee

• Warsaw Orthopedic, Inc.

Inventors

• Jeffrey M. Gross · Carlsbad, US
• Steve Peckham · Memphis, US
• Jeffrey L. Scifert · Arlington, US
• Jeffrey Badura · Memphis, US
• Nelson L. Scarborough · Andover, US
• Scott M. Vickers · Hernando, US

Key dates

• Filing date: Dec 4, 2007
• Grant date: Jun 16, 2015
• Expiry date: Dec 3, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.