Patent · US Active

Process for preparing sodium salts or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylate

US9056848B2 · kind B2 · utility

0Cited by

3References

13Claims

0Family size

Assignee

Bayer Intellectual Property GmbH · DE

Inventors

Christian Funke · Leichlingen, DE
Taraneh Farida · Pulheim, DE
Stefan Beeck · Meerbusch, DE
Norbert Lui · Odenthal, DE
Berndt Maiwald · Kirchberg, DE

Key dates

Filing date	Feb 29, 2012
Grant date	Jun 16, 2015
Priority date	—
Expiry date	Feb 29, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D307/68
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Process for preparing sodium or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylic esters, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the formula (III)which is then reacted further with a chloroacetic ester to give a compound of the formula (V)followed by a ring closure reaction in which the compound of the formula (V) is reacted with a sodium or potassium alkoxide of the formula ZOR1 where R1, R2, R3 and K are each as defined in the description.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.