Method for producing retrovirus using human producer cells with increased N-acetylglucosaminyltransferase III activity
US9057056B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Sep 28, 2005 |
| Grant date | Jun 16, 2015 |
| Priority date | — |
| Expiry date | Nov 7, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The N-acetylglucosaminyltransferase III activity is enhanced in a cell carrying retrovirus-origin gag-pol gene and env gene. By constructing a retrovirus vector with the use of the above cell, a retrovirus vector having a modified sugar chain structure can be obtained. The retrovirus vector constructed by this method shows a high infection efficiency particularly in the presence of a functional substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.