Neuropeptide Q as modulator of GPCR GALR2 and uses thereof
US9057726B2 · kind B2 · utility
2Cited by
6References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 23, 2011 |
| Grant date | Jun 16, 2015 |
| Priority date | — |
| Expiry date | Nov 3, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to the identification of Neuropeptide Q as ligand of the GALR2 GPCR (G-protein coupled receptor). The invention encompasses the use of the interaction of GALR2 polypeptides and Neuropeptide Q polypeptides as the basis of screening assays for agents that modulate the activity of the GALR2 receptor. The invention also encompasses diagnostic assays based upon the GALR2/Neuropeptide Q polypeptide interaction, as well as kits for performing diagnostic and screening assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.