Intravascular delivery of nanoparticle compositions and uses thereof
US9061014B2 · kind B2 · utility
37Cited by
41References
18Claims
0Family size
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Key dates
| Filing date | Apr 27, 2012 |
| Grant date | Jun 23, 2015 |
| Priority date | — |
| Expiry date | Aug 1, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/0089
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.