Stabilized STAT3 decoy oligonucleotides and uses therefore
US9062121B2 · kind B2 · utility
1Cited by
18References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 2014 |
| Grant date | Jun 23, 2015 |
| Priority date | — |
| Expiry date | Apr 4, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.