Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases

US9062301B2 · kind B2 · utility

Assignees

• aTyr Pharma, Inc. · US
• Pangu BioPharma Limited · CN

Inventors

• Leslie Ann Greene · San Diego, US
• Kyle P. Chiang · Irvine, US
• Fei Hong · San Diego, US
• Alain P. Vasserot · South San Francisco, US
• Jeffry D. Watkins · Encinitas, US
• Cheryl L. Quinn · Minneapolis, US
• Wing-Sze Lo · Hong Kong, CN
• John D. Mendlein · Encinitas, US

Key dates

• Filing date: May 4, 2011
• Grant date: Jun 23, 2015
• Expiry date: Jul 9, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.