Methods and systems of optical imaging for target detection in a scattering medium
US9066657B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 23, 2010 |
| Grant date | Jun 30, 2015 |
| Priority date | — |
| Expiry date | Aug 29, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/0064
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for enhancing contrast in fluorescence imaging is provided. The method comprises providing a patterned illumination source for illuminating one or more regions corresponding to a scan step, scanning at least a portion of a surface of a subject using a plurality of scan steps, acquiring image frames corresponding to two or more scan steps, deducting a background fluorescence from the image frames corresponding to the two or more scan steps to form one or more processed image frames, and reconstructing an image using one or more of the processed image frames.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.