Methods of treating breast cancer with anthracycline therapy

US9066963B2 · kind B2 · utility

Assignees

• The University of North Carolina at Chapel Hill · US
• Washington University · US
• University of Utah Research Foundation · US
• British Columbia Cancer Agency Branch · CA

Inventors

• Charles M. Perou · Chapel Hill, US
• Matthew J. Ellis · Romsey, GB
• Philip S. Bernard · Salt Lake City, US
• Torsten O. Nielsen · North Vancouver, CA

Key dates

• Filing date: Mar 15, 2012
• Grant date: Jun 30, 2015
• Expiry date: Mar 15, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including anthracycline and administering the therapy in subjects when it is found that anthracycline is likely to be effective.