Chemical process for opening ring compounds
US9067868B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Jul 25, 2012 |
| Grant date | Jun 30, 2015 |
| Priority date | — |
| Expiry date | Jul 25, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C231/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
It is described a process for the opening of lactone or lactam rings useful in the synthesis of pharmaceutically active compounds and the intermediates thereof, particularly Aliskiren. It has found that by selecting a type of solvent it is possible to obtain excellent yields and high optical and chemical purity of the isolated products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.