Methods of using voltage-gated Hv1 proton channels to detect changes in intracellular pH
US9068018B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Feb 15, 2007 |
| Grant date | Jun 30, 2015 |
| Priority date | — |
| Expiry date | Mar 27, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6872
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Nucleic acid and protein sequences relating to a proton channel (Hv1) are disclosed. Nucleic acids, vectors, transformed cells, transgenic animals, polypeptides, and antibodies relating to the Hv1 gene and protein are disclosed. Also provided are methods of identifying modulators of Hv1 activity, methods of geno typing subjects with respect to Hv1, and methods of diagnosing and treating Hv1-mediated disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.