Microassembled imaging flow cytometer
US9068916B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 3, 2011 |
| Grant date | Jun 30, 2015 |
| Priority date | — |
| Expiry date | Mar 18, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/6428
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A microassembled imaging cytometer includes a sensing location that undergoes relative motion with a cell. Light from a light source is focused by a focusing element to a plurality of focused illumination spots or lines at the sensing location, illuminating the cell as the cell traverses the sensing location. A collection lens collects light emanating from the cell and refocuses the collected light onto an array light sensor. The focusing element may include an array of microlenses having spherical or aspheric surfaces. The system may include a processing unit that constructs a digital image of the cell based at least in part on signals produced by the array light sensor indicating the intensity and distribution of light falling on the array light sensor. The system may characterize cells using light emanating from the cells by fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.