Patent · US Active

Methods of treating obesity by inhibiting nicotinamide N-methyl transferase (NNMT)

US9072766B2 · kind B2 · utility

5Cited by
0References
34Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 18, 2011
Grant dateJul 7, 2015
Priority date
Expiry dateNov 18, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/321
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention, in various embodiments, relates to methods of inhibiting NNMT production or activity in a cell, and methods of treating or preventing obesity or a related metabolic condition in a subject in need thereof, comprising administering a nicotinamide N-methyltransferase (NNMT) antagonist. The invention further provides methods of identifying NNMT antagonists useful for treating obesity and related metabolic disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.