Treatment regimen for N-MYC, c-MYC, and L-MYC amplified and overexpressed tumors
US9072778B2 · kind B2 · utility
11Cited by
2References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 20, 2006 |
| Grant date | Jul 7, 2015 |
| Priority date | — |
| Expiry date | Jun 29, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions for treating diseases. More specifically, the present invention relates to the administration of multiple drugs as part of a treatment of disease. Specific embodiments of the invention relate to a treatment regimen for neuroblastomas and other N-MYC, c-MYC, and L-MYC amplified and overexpressed tumors, comprising administering multiple therapeutic compounds like DFMO, SAM486A, a verinoid and a cytotoxic drug and placing the patient on a low polyamine diet and/or providing the patient with a polyamine limiting dietary supplement.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.