Patent · US Active

2-amino-4-arylthiazole compounds as TRPA1 antagonists

US9073955B2 · kind B2 · utility

0Cited by

6References

6Claims

0Family size

Assignee

Glenmark Pharmaceuticals S.A. · CH

Inventors

Sukeerthi Kumar · Navi Mumbai, IN
Abraham Thomas · Jamkhed, IN
Sachin Sundarlal Chaudhari · Jamkhed, IN
Bipin Parsottam Kansagra · Ahmedabad, IN
Venkata Ramana Yemireddy · Navi Mumbai, IN
Neelima Khairatkar-Joshi · Thane, IN
Indranil Mukhopadhyay · Navi Mumbai, IN
Girish Gudi · Mumbai, IN

Key dates

Filing date	Oct 21, 2013
Grant date	Jul 7, 2015
Priority date	—
Expiry date	Oct 21, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/65616
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is related to 2-amino-4-arylthiazole derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.