Patent · US Active

Immunopotentiative composition

US9073994B2 · kind B2 · utility

139Cited by
27References
30Claims
0Family size

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Key dates

Filing dateNov 21, 2014
Grant dateJul 7, 2015
Priority date
Expiry dateNov 21, 2034

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compositions for cancer or infection treatment via immunopotentiation caused by inhibition of immunosuppressive signal induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient, screening methods of the substrates for cancer or infection treatment, cell lines used for the screening methods, evaluation methods that selects the substrates for cancer treatment, and carcinoma cell transplanted mammals used for the evaluation methods.The compositions of the present invention that inhibits the function of PD-1, PD-L1, or PD-L2 are useful for cancer or infection treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.