Variants of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase

US9074229B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Alexander Reth · Bielefeld, DE
• Brigitte Bathe · Salzkotten, DE
• Stephan Hans · Osnabrück, DE
• Wilfried Claes · Bielefeld, DE

Key dates

• Filing date: Jan 28, 2015
• Grant date: Jul 7, 2015
• Expiry date: Jan 28, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.