Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions
US9075041B2 · kind B2 · utility
9Cited by
6References
35Claims
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Key dates
| Filing date | Jul 6, 2012 |
| Grant date | Jul 7, 2015 |
| Priority date | — |
| Expiry date | Aug 30, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5306
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological sample in a biosensor having a multisite array of test sites. In particular, the methods modulate the pH or ionic concentration gradient near the electrodes in such biosensor. The methods of modulating the binding interactions provide a biosensor and analytic methods for more accurately measuring an analyte of interest in a biological sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.