Cytoprotective agent

US9078880B2 · kind B2 · utility

Assignees

• NATIONAL UNIVERSITY ORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY · JP
• TMS CO., LTD. · US
• SHOWA UNIVERSITY · JP

Inventors

• Kazuo Honda · Saitama, JP
• Terumasa Hashimoto · Kawasaki, JP
• Keita Shibata · Tokyo, JP
• Keiko Hasegawa · Kasai, JP
• Keiji Hasumi · Inagi, JP

Key dates

• Filing date: Feb 5, 2010
• Grant date: Jul 14, 2015
• Expiry date: Feb 5, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed is a cytoprotective agent for use with respect to ischemic damage, including as an active ingredient a triprenyl phenol compound represented by the following general formula (I), wherein X is —CHY—C(CH3)2Z, Y and Z are each independently —H or —OH, or jointly form a single bond, and R represents a hydrogen atom or a substituent with a molecular weight of 1000 or less.