ε-Polylysine conjugates and the use thereof

US9078929B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Armin Kuebelbeck · Bensheim, DE
• Gregor Larbig · Gelnhausen, DE
• Walter Mier · Bensheim, DE
• Barbro Beijer · Schallstadt, DE
• Uwe Haberkorn · Schwetzingen, DE

Key dates

• Filing date: Jul 9, 2010
• Grant date: Jul 14, 2015
• Expiry date: Dec 17, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to ε-polylysine conjugates, in particular conjugates of ε-polylysine with compounds carrying carboxyl groups, and to the preparation and use thereof for targeting of the kidney.