Patent · US Active

NMDA receptor antagonists for neuroprotection

US9079852B2 · kind B2 · utility

1Cited by

111References

23Claims

0Family size

Assignees

EMORY UNIVERSITY · US
NEUROP, INC. · US

Inventors

Dennis C. Liotta · Atlanta, US
James P. Snyder · Atlanta, US
Stephen F. Traynelis · Decatur, US
Lawrence Wilson · Mason, US
Cara Mosley · Atlanta, US
Raymond J. Dingledine · Atlanta, US
Scott Myers · Atlanta, US
Yesim Altas Tahirovic · Atlanta, US

Key dates

Filing date	Apr 15, 2013
Grant date	Jul 14, 2015
Priority date	—
Expiry date	Apr 15, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D295/088
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided:wherein:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.