Patent · US Active

(4-phenylimidazol-2-yl) ethylamine derivatives useful as sodium channel modulators

US9079878B2 · kind B2 · utility

5Cited by
1References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 15, 2012
Grant dateJul 14, 2015
Priority date
Expiry dateOct 15, 2032

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I):or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators are useful in the treatment of a wide range of disorders, particularly pain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.