Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
US9080179B2 · kind B2 · utility
9Cited by
6References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 29, 2013 |
| Grant date | Jul 14, 2015 |
| Priority date | — |
| Expiry date | Apr 29, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A high flux of metabolites from pyruvate to 2,3-butanediol in Lactobacillus plantarum was achieved through genetic engineering. Substantial elimination of lactate dehydrogenase activity in the presence of heterologously expressed butanediol dehydrogenase activity led to 2,3 butanediol production that was at least 49% of the total of major pyruvate-derived products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.