Voltage offset correction in high-throughput electrophysiological measurement system
US9080999B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2012 |
| Grant date | Jul 14, 2015 |
| Priority date | — |
| Expiry date | Mar 19, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48728
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A computer-implemented method for controlling command voltages applied to electrodes during an electrophysiology measurement procedure using a high-throughput measurement system is provided. An initial command voltage is applied to the electrodes to obtain baseline currents respectively associated with the electrodes. A common offset voltage is determined based on the baseline currents, and an adjusted command voltage is determined based on the initial command voltage and the common offset voltage. The adjusted command voltage is applied to at least one of the electrodes to obtain an adjusted current measured by the electrode. A local offset voltage for the electrode is determined based on the adjusted current measured by the electrode. A subsequent command voltage applied to the electrode incorporates the common offset voltage and the local offset voltage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.